Work

Silver Nanoclusters with Broad-Spectrum Antibacterial Properties

Year: 2025

Type: article

Abstract: Bacterial resistance to antibiotics is a significant threat to global health, and innovative strategies are needed to tackle these bacterial infections. In this study, we used an in vitro bactericidal assay to demonstrate that small silver nanoclusters (AgNCs) coated with 5-mercapto-2-nitrobenzoic acid (MNBA) exhibit bactericidal activity against a range of Gram-negative and Gram-positive ESKAPEE bacteria and bacteria belonging to the WHO Priority Pathogen List. Understanding the broad-spectrum antibacterial properties of MNBA-AgNCs highlights the importance of nanoparticle customization in further combating antimicrobial resistance.

Source: ACS Omega

DOI: 10.1021/acsomega.5c00163

Authors: India J. Cook, Maria Eleni Kyriazi, Myron Christodoulides, Antonios G. Kanaras

Institutions: University of Southampton, American University of the Middle East, National and Kapodistrian University of Athens

Language: English

Topic: Nanocluster Synthesis and Applications

Subfield: Materials Chemistry

Field: Materials Science

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,935