Recurrent Spontaneous Subdural Hematoma in a Patient With Severe Hemophilia A: a Case Report and Clinical Reflections From a Resource-limited Setting
Year: 2025
Type: article
Study design: Case Report
Abstract: Background: Intracranial hemorrhage (ICH) is one of the gravest complications in hemophilia, often leading to significant neurological morbidity and mortality. Spontaneous subdural hematomas (SDHs) are especially rare and pose diagnostic and therapeutic dilemmas in patients with severe coagulation defects. Case Presentation: We report a 31-year-old male with genetically confirmed severe Hemophilia A who developed recurrent spontaneous SDHs without antecedent trauma. The patient was managed conservatively with recombinant factor VIII concentrate and neurocritical care monitoring, resulting in clinical stabilization and radiological improvement. Conclusion: This case underscores the critical need for high clinical vigilance, early imaging, and aggressive factor replacement in preventing progression of hemorrhagic events in hemophilia. Structured hemophilia care networks and access to prophylactic therapy remain indispensable in resource-limited countries such as India.
Author: Athulya G. Asokan
Language: English
Subfield: Hematology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W4411396219