Year: 2025
Type: article
Abstract: The Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL) it’s a genetic disorder that affects the small blood vessels in the brain for a pathological variant in the NOTCH3 gene, located on chromosome 19. It is of great interest to know its correct diagnosis based on expression and variable clinical symptomatology due to episodes of migraine, dementia, cerebral ischemic episodes, psychiatric disorders and motor difficulties. Factors involved in the differential diagnosis of this genetic disorder will be discussed, based on general international criteria like Neuroimaging Findings and Genetic Testing. In addition, its clinical manifestations will be analyzed in various patient contexts to identify specific features related to individual genetic variations.
Institution: Universidad Juárez del Estado de Durango
Language: English
Subfield: Neurology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W4411397452