Work

PARP1-NFATc1-PD1 pathway of maturation and stability of CD8+T cells is beneficial against chronic Trypanosoma cruzi infection

Year: 2025

Type: article

Abstract: infection. We conclude that molecular and chemical inhibitors of PARP1 would offer a potential therapy to arrest CD pathogenesis.

Source: iScience

DOI: 10.1016/j.isci.2025.112926

Authors: Imran H. Chowdhury, Nandadeva Lokugamage, Nisha J. Garg

Institution: The University of Texas Medical Branch at Galveston

Language: English

Topic: Trypanosoma species research and implications

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,240

Funders: Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, University of Texas Medical Branch at Galveston, National Institute of Allergy and Infectious Diseases

Awards: G1625110152, G1640144576, G1976640106, G8229320489

OpenAlex ID: W4411399272

FWCI: 1.869

Cites: 44

Cited by: 3

Related to: 10