Work

Phenotypic and genotypic profile of multiresistant bacterial strains from the Laboratory Surveillance Network of the State of Pará (LACEN/PA)

Year: 2025

Type: article

Abstract: Antibiotic resistance has reached alarming proportions since the COVID-19 pandemic due to the indiscriminate use of antibiotics. This phenomenon is already being identified as one of the greatest global threats of the century. In light of this, the objective of this article was to evaluate the phenotypic and genotypic profile of multidrug-resistant strains of Gram-negative bacilli (GNB) from the Central Laboratory of the State of Pará (LACEN-PA) during the period from 2019 to 2022. Phenotypic identification and antimicrobial resistance profile were analyzed using the automated VITEK® 2 bioMérieux method. The results showed that 55.7% of the isolated strains were fermenting Gram-negative bacilli (GNB-F) and 44.3% were non-fermenting Gram-negative bacilli (GNB-NF). Klebsiella pneumoniae was the most isolated bacterium (46%), followed by Pseudomonas aeruginosa (23.1%), Acinetobacter baumannii (19.9%), and Enterobacteriaceae (9.7%). The resistance genes found in K. pneumoniae were blaKPC and blaNDM; in P. aeruginosa, they were blaSPM, blaKPC, blaIMP, and blaNDM; in A. baumannii, they were blaOXA-23, blaIMP, blaNDM, blaOXA-14.

Source: Contribuciones a las Ciencias Sociales

DOI: 10.55905/revconv.18n.6-186