Work

Ocular Pharmacokinetics and Biodistribution of Perfluorohexyloctane after Topical Administration to Rabbits

Year: 2025

Type: article

Abstract: Exposure of PFHO was highest in tears, consistent with its anti-evaporative mode of action, followed by the Meibomian glands. PFHO exposure was very low in posterior ocular tissues and negligible in systemic circulation, consistent with the clinical safety profile.

Source: Journal of Ocular Pharmacology and Therapeutics

DOI: 10.1089/jop.2025.0056

Authors: Sonja Krösser, Ralf Grillenberger, Kirsten Eickhoff, Johannes Korward, Megan E. Cavet, Francis S. Mah

Institutions: Novaliq (Germany), Scripps Health

Language: English

Topic: Ocular Surface and Contact Lens

Subfield: Public Health, Environmental and Occupational Health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W4411404048

FWCI: 1.699

Cites: 27

Cited by: 2

Related to: 10