Physiological plasticity in zebra finch color varieties mitigates DNA damage under oxidative stress
Year: 2025
Type: article
Abstract: individuals exhibited higher DNA damage and a gene expression profile compatible with cellular redox imbalance. During oxidative stress, these birds minimized DNA damage and changed pheomelanin concentration, consistent with cysteine/glutathione economization. Further analyses revealed downregulation of glutathione S-transferases in pheomelanic morphs across species. We propose that pheomelanic birds might have an adaptive built-in physiological plasticity under environmental oxidative stress.
Source: iScience
Authors: Cristiana I. Marques, Sol Rodríguez-Martínez, Pedro Miguel Araújo, Sandra Afonso, Marina Córdoba-Aceituno, Mohammed Zougagh, Ángel Ríos, Miguel Carneiro, Ismael Galván
Language: English
Subfield: Cell Biology
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $3,240
Awards: G1175115578, G121809054, Rede de Investigação em Biodiversidade e Biologia Evolutiva (InBIO), G1855990336, G2262748287, G2309174360, G262436378, G2660406951, G279363373, G300979063, G308504231, G3288447102, G34346518, G3480869486, Evolutionary genetics and genomics of learned vocal behaviour in songbirds, G425668148, G430777504, G4338831617, G4630152088, G5051979045, G5080475149, The Colour of Cooperation: linking colour polymorphism to mutualistic behaviour in the Caribbean sharknose cleaning goby (Elacatinus evelynae), G5385376234, G5421974903, G5577226636, G5797619550, G5805502524, G6300758260, G7084143925, G8920660035, G897484643, G9000109305, G99296377
OpenAlex ID: W4411404155