Work

Quantitative Measurement of Tau Burden in a Dual-Time-Window Dynamic PET Imaging Protocol with [18F]MK6240

Year: 2025

Type: article

Abstract: F]MK6240. Such a protocol would be well suited to allow for both quantification of tau and derivation of an index of cerebral perfusion while reducing patient discomfort and increasing scanning efficiency in comparison to a full dynamic acquisition.

Source: Journal of Nuclear Medicine

DOI: 10.2967/jnumed.125.270165

Authors: Ye Xia, Maeva Dhaynaut, Yanis Chemli, Cristina Lois, Bernard J. Hanseeuw, Emma Thibault, Colin Groot, Rik Ossenkoppele, Keith Johnson, Georges El Fakhri, Marc D. Normandin, Nicolas J. Guehl

Institutions: Harvard University, Massachusetts General Hospital, Vrije Universiteit Amsterdam, Amsterdam UMC Location Vrije Universiteit Amsterdam, Yale University, Cliniques Universitaires Saint-Luc, UCLouvain, Amsterdam Neuroscience, Amsterdam University Medical Centers, Lund University

Language: English

Topic: Medical Imaging Techniques and Applications

Subfield: Radiology, Nuclear Medicine and Imaging

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, National Institute on Aging, National Institute of Biomedical Imaging and Bioengineering

Awards: G1165789932, G3034196725, G4170966788, Center for Molecular Imaging Technology & Translation (CMITT), Methods for Quantitative Neuroimaging of Tau Burden in Pre-symptomatic AD

OpenAlex ID: W4411410233

FWCI: 0.528

Cites: 42

Cited by: 1

Related to: 10