Work

Ewing’s sarcoma of the mediastinal extraosseous site: a case report of a rare occurrence with literature review

Year: 2025

Type: article

Abstract: Objective: To present a rare case of mediastinal extraosseous Ewing sarcoma(EES), broadening the body of knowledge already in existence on EES. This paper intends to give doctors more diagnostic and therapeutic understanding. Methods: The patient's imaging data was analyzed retrospectively. We identified and compiled the distinctive imaging characteristics of mediastinal EES by combining these results with histopathological evaluation and a review of relevant literature. Key findings: Typical imaging features of mediastinal EES include a large, bulky mass with irregular shape and lobulated, poorly defined margins. On computed tomography (CT), it often shows heterogeneous density along with infiltration of nearby organs and anatomical structures. Conclusion: Mediastinal EES is a rare and clinically challenging diagnosis. However, recognition of its characteristic imaging features may facilitate radiological diagnosis. Nevertheless, histopathological confirmation remains the gold standard for definitive diagnosis.

Source: Frontiers in Oncology

DOI: 10.3389/fonc.2025.1578456

Authors: Hong Zhou, Meng Su, Han-Fang Wang, Si-Qi Feng, Wen-Qian Jiang, Xiao-Rong Li

Institution: Chinese People's Liberation Army

Language: English

Topic: Sarcoma Diagnosis and Treatment

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,801