Work

On the synthesis and structure of reactive halonium ions

Year: 2025

Type: article

Abstract: Fluorinated diethyl and dipropyl halonium salts were synthesized via fluoroalkylation of bromofluoro and iodofluoro alkanes. Oxidation of CHCl(CH 3 )(CF 3 ) yielded a highly reactive asymmetric chloronium species, capable of isobutane activation.

Source: Chemical Science

DOI: 10.1039/d5sc03756e

Authors: Lukas Fischer, Michael H. Lee, Anja Wiesner, Carsten Müller, Sebastian Riedel

Institution: Freie Universität Berlin

Language: English

Topic: Fluorine in Organic Chemistry

Subfield: Pharmaceutical Science

Field: Pharmacology, Toxicology and Pharmaceutics

Domain: Life Sciences

Open Access status: diamond

Funders: Deutsche Forschungsgemeinschaft, Freie Universität Berlin, H2020 European Research Council, FP7 Ideas: European Research Council

Awards: G2219973697, G3645873082, SFB 1349: FluorSpezifische Wechselwirkungen: Grundlagen und Anwendungen, Exploring the Limits of High Potential Oxidizers Prediction, Validation and Preparation of Unusual Molecules at the Edge of Stability