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Proteoglycan-4 (PRG4) serum concentration is lower in aged mice, and genetic deficiency impacts survival probability, blood parameters, and bone during aging

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Year: 2025
Type: article
Source: GeroScience
DOI: 10.1007/s11357-025-01747-x
Authors: Adam P. Tanguay, Nikhil G. Menon, Emma Slavin, Mikayla Moody, Erin McEwen, Gregory D. Jay, Joseph Lorenzo, Jenna M. Bartley, Vanessa M. Scanlon, Alix C. Deymier, Tannin A. Schmidt
Institutions: UConn Health, Brown University
Language: English

Topic: Proteoglycans and glycosaminoglycans research
Subfield: Cell Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, National Institute of Allergy and Infectious Diseases, National Institute of Diabetes and Digestive and Kidney Diseases
Awards: The Role of Intrinsic and Extrinsic Factors in Megakaryocytic-Erythroid Progenitor Lineage Commitment, G6662175378, G8964332032, Impact of Senolytics on Aged Vaccine Responses
OpenAlex ID: W4411438149
FWCI:
Cites: 54
Cited by:
Related to: 10
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