2D Shear Wave Elastography: An Evolving Technique for Comparison of Placental Elasticity in Normal and Preeclamptic Pregnancy
Year: 2025
Type: article
Study design: Observational Study
Abstract: Objective: This article evaluates differences in placental elasticity between normal and preeclamptic pregnancies using shear wave elastography and assesses the potential of the placental elasticity values in predicting preeclampsia. Materials and Methods: The study included 60 pregnant women, 30 diagnosed with preeclampsia and 30 with normal pregnancies, in their second and third trimesters. Shear wave elastography was performed to assess placental elasticity. Both mean (average) and maximum elasticity values were recorded and cutoff values were determined using receiver operating characteristic (ROC) curve analysis to evaluate their potential in predicting preeclampsia. Results: < 0.0001). In preeclampsia cases, the shear wave modulus was higher in the central region of the placenta than at the edges. ROC curve analysis evaluated a mean elasticity cutoff value of 8.1 kPa, with a sensitivity of 100%, specificity of 96.67%, positive predictive value of 96.8%, negative predictive value of 100%, and a diagnostic accuracy of 98.33%. Conclusion: The study revealed significant differences in placental elasticity between preeclamptic and healthy pregnancies, highlighting the potential of shear wave elastography as a valuable tool for early prediction of preeclampsia. Early prediction using this method could significantly reduce maternal and perinatal mortality and morbidity, especially in developing countries, by identifying cases before the onset of clinical symptoms.
Authors: Ritika Sihmar, Shahina Bano, Renuka Malik
Language: English
Subfield: Radiology, Nuclear Medicine and Imaging
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4411439395