Rapid and Multiplex Diagnosis of Malaria Using Chelex-100 Extraction and LAMP-MS Assay
Year: 2025
Type: article
Abstract: (Pv), pan-malaria (Pan), and an internal control (IC) within 40 min, from DNA extraction to result interpretation. It demonstrates sensitivity and specificity comparable to traditional PCR-based diagnostics, making it a practical and scalable solution for use in resource-constrained environments. Key features • Low-cost and simple DNA extraction using Chelex-100 resin. • Multiplex detection of Pan malaria, Pf, Pv, and IC using microchip chambers. • Visual endpoint detection using a microscope or a microscanner. • Field-deployable with minimal equipment.
Source: BIO-PROTOCOL
Authors: Min Lim, Young Choe, Woong Jang
Institutions: Korea University, Korea University Guro Hospital
Language: English
Topic: Malaria Research and Control
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4411440594