Work

Taste disorders due to unilateral upper molar extraction in juvenile and adult albino rats

Year: 2025

Type: article

Abstract: Introduction The sense of taste is fundamental to life; some studies have revealed a link between dental deafferentation (DD) by upper molar extraction and taste abnormalities in rats. However, no studies have been found that evaluate these variables using the Taste Reactivity Test (TRT). Methods Forty male Wistar rats (20 juveniles and 20 adults) were used and assigned to a control and experimental group. Both groups were fitted with cannulae for TRT, while rats in the experimental group also had their right upper molars extracted. Using an ingestive solution (1 M sucrose) and an aversive solution (3 mM denatonium benzoate [BD]), TRT was performed on days 1, 7, 14, and 21. Body and orofacial reactions were recorded and scored. Results DD influences ingestive responses in juvenile rats at days 7, 14, and 21; however, it only affects aversive responses at day 21. In adult rats, it influences ingestive responses at days 14 and 21, although it only affects aversive responses at day 14. When comparing ingestive and aversive responses between juvenile and adult rats in the experimental group, differences were identified in ingestive responses at days 7 and 14. Conclusions In juvenile and adult rats, upper molar extraction has a negative influence on ingestive and aversive responses. In addition, compared to adult rats, it has a negative effect on ingestive responses in juvenile rats.

Source: Neurology Perspectives

DOI: 10.1016/j.neurop.2025.100203

Authors: A. Gutiérrez-Patiño Paúl, E. Aguirre-Siancas

Institution: National University of San Marcos

Language: English

Topic: Biochemical Analysis and Sensing Techniques

Subfield: Nutrition and Dietetics

Field: Nursing

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,430