The interaction of Candida albicans and Helicobacter pylori as a probable impossibility of achieving the goals of eradication therapy: A clinical case
Year: 2025
Type: article
Study design: Case Report
Abstract: The presented clinical case examines the interaction between two microorganisms, Candida albicans and Helicobacter pylori, and their possible impact on the effectiveness of eradication therapy. Eradication therapy is a set of measures aimed at destroying pathogenic microorganisms in the human body. However, in some cases, achieving complete eradication may be difficult due to interactions with other microorganisms, such as Candida. In the presented clinical case, we are faced with a situation where standard eradication therapy regimens do not allow for complete elimination of H. pylori. The patient has both C. albicans and H. pylori, which can lead to deterioration of the condition and lack of remission of symptoms. In addition, antibiotic resistance may develop. When eradication therapy is prescribed, the patient notes a decrease in clinical symptoms, while a repeat test for H. pylori is positive. After the additional examination (stool for dysbacteriosis with determination of sensitivity to antibacterial drugs, antibodies to parietal cells of the stomach) the therapy was adjusted due to the detection of C. albicans with subsequent control of laboratory parameters to assess the effectiveness of the prescribed therapy. Repeated analysis for H. pylori showed positive dynamics, which indicates the correct choice of patient management tactics. In this regard, it can be concluded that timely diagnosis of candidiasis plays an important role in increasing the effectiveness of treatment and improving the quality of life of a patient with chronic gastritis. This clinical case emphasizes the importance of taking into account the interaction between various microorganisms during eradication therapy. This can help increase its effectiveness and improve the treatment results for patients with infections caused by Helicobacter pylori.
DOI: 10.21518/ms2025-097
Language: English
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4411446226