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Pancytopenia Unraveled: Tracing Rare Cardiobacterium hominis Bacteremia Back to the Gut

Year: 2025
Type: article
Study design: Case Report
Abstract: Cardiobacterium hominis (C. hominis) is part of the normal flora of the human oropharynx. Although uncommon, it is a significant cause of endocarditis, particularly in individuals with pre-existing valvular heart disease. The combination of its rarity, prolonged blood culture incubation time, and nonspecific clinical presentation makes C. hominis infections particularly challenging to diagnose. We present the first known published case of pancytopenia secondary to C. hominis bacteremia in an elderly male, likely incited by a gastrointestinal endoscopic procedure. We discuss the importance of recognizing signs of subclinical bacteremia and maintaining a broad differential for pancytopenia for timely diagnosis and management.
Source: Cureus
Authors: Annie Kleynerman, Ryan C Day, Iiro Honkanen
Language: English
Subfield: Epidemiology
Field: Medicine
Open Access status: diamond
OpenAlex ID: W4411448904
FWCI: 0.623
Cites: 8
Cited by: 1
Related to: 10