Work

Elucidation of the acid reactivity of polyhedral orthoformates for the synthesis of carbasugar derivatives

Year: 2025

Type: article

Abstract: -inositols, the key synthetic intermediates of our study, exhibit differing reaction selectivities depending on their geometric isomerism and substituents. Here we present new insights that contribute to the synthesis of carbasugar-type derivatives by elucidating the mechanism of the selectivity using density functional theory (DFT) calculations.

Source: RSC Advances

DOI: 10.1039/d5ra01049g

Authors: Kazuki Usuguchi, Akira Takagi, Ippei Takashima, Kensuke Okuda

Institution: Kobe Pharmaceutical University

Language: English

Topic: Carbohydrate Chemistry and Synthesis

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: gold

Estimated APC paid: $1,042