Year: 2025
Type: article
Abstract: Describe the symptoms of gout, the number of deaths caused by gout, and the impact of gout in various countries, and analyze its pathogenic mechanisms. Treatment with two uric acid transporters, ABCG2 and SLC2A9, is used as drugs, from tracing the origin of ABCG2 and SLC2A9 to understanding their nomenclature and studying their chemical properties and then to the relationship between ABCG2 and SLC2A9 and gout, as well as the comparison of the mechanism of action of ABCG2 and SLC2A9. As a common disease with unclear pathogenic mechanisms, gout has limited drugs for treatment and large side effects; ABCG2 and SLC2A9 have obvious effects on gout by controlling the uric acid content in the body with almost no side effects.
Source: Theoretical and Natural Science
Author: Ziyu Rong
Language: English
Subfield: Nephrology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W4411457014