Year: 2025
Type: editorial
Abstract: ABSTRACT Cardiovascular disease (CVD) remains a leading cause of morbidity and mortality worldwide. Polyphenols, bioactive compounds found in plant‐based foods, exert cardioprotective effects, partly mediated by their interactions with the gut microbiome. This editorial explores how microbial metabolites of polyphenols enhance bioavailability and exert potent vascular benefits while also addressing polyphenols' potential role in reducing harmful metabolites such as trimethylamine N‐oxide (TMAO) and phenylacetylglutamine (PAGln). Despite promising preliminary findings, further research is required to elucidate underlying mechanisms and optimize polyphenol‐based interventions for cardiovascular health.
Source: Food Frontiers
DOI: 10.1002/fft2.70063
Authors: Kalpana Singh, Treesa Thomas
Institution: Hamad Medical Corporation
Language: English
Topic: Gut microbiota and health
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $3,700
Funder: Qatar National Library
OpenAlex ID: W4411458433