Work

Self-Assembled Molecular Glue Prodrug System for Enhanced Synergistic Tumor Therapy by Combining CDK12 Protein Degradation and Immunotherapy

Year: 2025

Type: article

Source: ACS Applied Materials & Interfaces

DOI: 10.1021/acsami.5c02939

Authors: Nan Zhang, Ruihao Li, Huaxing Shen, Huang Li, Siyao Liu, Hongli Liao, Wei Cong, Xiaochun Hu, Honggang Hu

Institutions: Shanghai University, Tongji University, Shanghai East Hospital, Chengdu Medical College

Language: English

Topic: Protein Degradation and Inhibitors

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

Funder: National Natural Science Foundation of China

Awards: G1374641574, β-catenin靶向性近红外光笼PROTAC探针的构建、抗肿瘤活性及机制研究

OpenAlex ID: W4411459709

FWCI: 1.567

Cites: 42

Cited by: 6

Related to: 10