Osmotic demyelination syndrome: A pediatric case report and a systematic literature review
Year: 2025
Type: article
Abstract: Osmotic Demyelination Syndrome (ODS) is a life-threatening neurologic disorder including two distinct types of demyelination: Central Pontine Myelinolysis (CPM) and Extrapontine Myelinolysis (EPM). While it's clear that the fast correction of low sodium levels is a key precipitating factor, the underlying pathophysiological mechanisms that cause ODS are still being explored. The present paper describes a case of an eleven-year-old male patient diagnosed with ODS based on typical imaging findings. This case report sounds like it could be significant by providing a thorough overview of the pathological findings, clinical outcomes, and imaging findings associated with this condition, particularly in pediatric cases. It also demonstrates the crucial role of MRI in diagnosing this condition.
Source: Radiology Case Reports
Authors: Y. Mouhcine, Z. Ezzoulali, H. Ouazzani, I. Chaouche, A. AKAMMAR, N. EL Bouardi, B. Alami, Y. Alaoui Lamrani, M. Maaroufi, M. Boubbou
Institution: Sidi Mohamed Ben Abdellah University
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $600
OpenAlex ID: W4411460780