Work

[18F]-fluorocholine long-axial-field of view PET-CT accurately localises intrathyroid parathyroid adenoma in 5-month pregnant patient

Year: 2025

Type: article

Abstract: The patient needed multiple hospitalisations and was at risk of foetal and maternal complications.Exploratory neck surgery was unsuccessful.We performed a low-dose PET-CT to minimise radiation exposure to the foetus [2].The patient was injected with 17 MBq (0.2 MBq/kg) and scanned for 30 min from vertex to diaphragm, 62 min post-injection using a Biograph Vision Quadra PET-CT (Siemens Healthineers, Erlangen, Germany).CT was performed with CAREDose on (reference mAs = 65), CAREkV reference 120 kV.[ 18 F]-fluorocholine LAFOV PET-CT demonstrated focal intense choline uptake in a low density intrathyroid left lower pole nodule, consistent with a parathyroid adenoma (A: MIP, B: axial CT and C: fused axial images).An uncorrected PET-only acquisition was performed to calculate the foetal dose, which was estimated at 0.5 mSv from PET and 0.1 mGy from CT.

Source: European Journal of Nuclear Medicine and Molecular Imaging

DOI: 10.1007/s00259-025-07417-6

Authors: Beverley F. Holman, Tamar Willson, Jane Edwards, Bruno Ferreira, Piyumi Wijewickrama, Thomas Wagner

Institutions: Royal Free London NHS Foundation Trust, University College London, Royal Sussex County Hospital, The Royal Free Hospital

Language: English

Topic: Radiation Dose and Imaging

Subfield: Radiology, Nuclear Medicine and Imaging

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $3,490