Work

Quantifying phage-bacteria dynamics in vitro: rapid emergence of phage-resistant mutants for Klebsiella pneumoniae

Year: 2025

Type: article

Abstract: alone and with the presence of bacteriophage vB_Kpn_2-P4. Using mathematical models we estimate key parameters for these experiments, showing the rapid growth and emergence of phage-resistant mutants which outcompete the susceptible bacteria strains. Our results provide quantitative estimates of these processes and may be useful for understanding phage-bacterial dynamical systems and parameterizing future theoretical and computational models.

Source: PubMed

DOI: 10.17912/micropub.biology.001666

Authors: Marcos Rodríguez, Irene Cantallops, Pilar Domingo-Calap, Josep Sardanyés

Institutions: Institute for Integrative Systems Biology, Centre de Recerca Matemàtica

Language: English

Topic: Bacteriophages and microbial interactions

Subfield: Ecology

Field: Environmental Science

Domain: Physical Sciences

Open Access status: green

OpenAlex ID: W4411468972

FWCI: 0.521

Cites: 15

Cited by: 1

Related to: 10