Work

Impact of Intermittent Fasting on Glycemic Control in Type 2 Diabetes: An Original Research

Year: 2025

Type: article

Study designs: Randomized Controlled Trial, Clinical Trial

Abstract: Background: "Type 2 diabetes (T2D)" requires effective glycemic control to prevent complications. "Intermittent fasting (IF)" is a potential lifestyle intervention that may improve glycemic outcomes, though evidence is still evolving. Objective: This study evaluated the impact of IF on glycemic control and metabolic health in T2D. Methods: One hundred adults with T2D were randomly assigned to an IF group (50 following an 8-h eating window) or a control group, non-dietary advice. The primary outcomes were glycated Hemoglobin A1c (HbA1C), and fasting glucose; secondary outcomes included "body mass index (BMI)" or waist circumference, a surrogate marker of central obesity, and insulin resistance by homeostasis model assessment-insulin resistance test (HOMA-IR). We performed hypothesis tests to test for changes within and between groups. Results: < 0.01). Conclusion: IF significantly improved glycemic control, body composition, and insulin sensitivity in T2D patients, indicating its potential as a non-pharmacological management strategy. Further research is recommended to explore long-term effects and IF regimen variations.

Source: Journal of Pharmacy And Bioallied Sciences

DOI: 10.4103/jpbs.jpbs_1582_24

Authors: Maarya Mohammed Siddiqi, Muneza Mariam Farhan, Moosa Mohammed Siddiqi, Mohammed Abdus Sami Amaan, Amaarah Ayesha Farhan, Afeefa Sufian

Institutions: Shadan Hospital and Institute of Medical Sciences, Deccan College of Medical Sciences

Language: English

Topic: Dietary Effects on Health

Subfield: Physiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $250