System readiness and the patient care pathway for Alzheimer's disease diagnosis and treatment
Year: 2025
Type: article
Abstract: Promising therapeutic interventions that target the underlying pathophysiology are changing the landscape of Alzheimer's disease (AD) research. The AD care pathway must be transformed to meet the challenge of bringing these new therapies to the increasing number of people living with AD within the existing healthcare framework. Challenges include identifying patients who may benefit from treatment interventions early in the course of the disease, ensuring that diagnostic tools are accessible and accurate, and developing capabilities to monitor the effectiveness of interventions over time. These challenges must be addressed at all levels, from primary care settings to tertiary treatment centers; this will require collaborative efforts between health systems, drug manufacturers, and research institutions to navigate this evolving landscape and ensure system readiness for patients and their families with AD. The Spring 2024 Alzheimer's Association Research Roundtable (AARR) meeting gathered industry representatives and clinicians to discuss insights, challenges, and solutions that will help researchers and health systems identify patients in the early stages of AD and deliver emerging therapies efficiently and safely. In this paper, we provide highlights from the Spring 2024 AARR meeting.
DOI: 10.1002/trc2.70094
Authors: B. Joy Snider, Alessandro Biffi, Sasha Bozeat, Carolyn Clevenger, Gill Farrar, Darren Gitelman, Rachel Kolster, Soeren Mattke, Michelle Mielke, Debjani Mukherjee, Jennifer Murphy, Hamid Okhravi, Gil D. Rabinovici, Dorene Rentz, Jose Soria, Heather Synder, Gregg Walker, Simin Mahinrad, Maria C. Carrillo, Christopher J. Weber
Institutions: Washington University in St. Louis, Hope Center for Neurological Disorders, Eli Lilly (United States), Roche (Switzerland), Emory University, Woodruff Health Sciences Center, Advocate Lutheran General Hospital, University of Southern California, Wake Forest University Health Sciences, Wake Forest University, Biogen (United States), Eastern Virginia Medical School, University of California, San Francisco, Brigham and Women's Hospital, Harvard University, UC San Diego Health System, University of California San Diego, NeuroVita Clinic, Alzheimer's Association
Language: English
Subfield: Psychiatry and Mental health
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,540
OpenAlex ID: W4411501157
