Perioperative analgesic efficacy of quadratus lumborum block versus transversus abdominis plane block in dogs undergoing laparoscopic ovariectomy: a prospective randomized clinical trial
Year: 2025
Type: article
Abstract: Introduction: This prospective randomized study (protocol number 0156185) aims to evaluate the perioperative analgesic efficacy of quadratus lumborum block (QLB) versus transversus abdominis plane block (TAPB) in dogs undergoing elective laparoscopic ovariectomy. Materials and methods: Dogs premedicated with methadone (0.2 mg/kg IV), inducted with propofol and maintained under general anesthesia with isoflurane were randomized into 3 groups. In the QLB group, 0.5 mL/kg of ropivacaine 0.35% was administered at L1-L2 bilaterally; in the TAPB group, 0.25 mL/kg of ropivacaine 0.35% per injection was administered in four sites; the third group, named P, was a control group where dogs did not receive any block. Heart rate (HR), invasive mean arterial pressure (MAP) and end-tidal concentration of isoflurane (etISO) were recorded at surgical timepoints: pre-stimulus baseline (T0), skin and abdominal wall incision (T1), induction of capnoperitoneum (T2), traction and ligation of the right (T3) and left ovaries (T4). Intraoperative data collection and adjustment of the hypnotic plan were performed by an operator blinded to the used technique. Cardiovascular response (CR) was defined as a 20% increase in MAP and/or HR from T0. Dogs with MAP greater than 30% of baseline received an infusion of remifentanil (0.5 mcg/kg/min) and were recorded as intraoperative rescue analgesia (iRA) events. Postoperative analgesia was assessed with Glasgow Composite Measure Pain Scale short form (GCMPS-SF) at 2 and 4 h after extubating. Results: = 0.001). No patient received postoperative rescue analgesia. Conclusion: Both TAPB and QLB guaranteed adequate analgesia regarding the somatic stimulus (T1) compared to P whereas all groups were not able to prevent a cardiovascular response during the induction of capnoperitoneum (T2) and ovarian traction (T3-T4). Analgesia in the early postoperative period (up to 4 h) was adequate in all groups.
Source: Frontiers in Veterinary Science
Authors: Eleonora Fumanelli, Giorgia Cocca, Giorgia Giannetti, Marianna Parabella, Roberto Rabozzi, Diego Sarotti
Language: English
Subfield: Small Animals
Field: Veterinary
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $3,801
OpenAlex ID: W4411501940