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Atypical tinea corporis with Id reaction: A case report and successful treatment with upadacitinib

Year: 2025
Type: article
Study design: Case Report
Abstract: Atypical tinea corporis, characterized by clinical manifestations that resemble other skin disorders, can lead to misdiagnosis and delayed treatment. This 67-year-old male had a seven-month history of pruritic skin lesions resembling subcorneal pustular dermatosis. Dermatological exam and fungal culture confirmed Trichophyton rubrum -induced atypical tinea corporis. After oral itraconazole treatment, he developed symmetrical eczematous lesions (Id reaction) on his extremities. Initial treatment was ineffective, so upadacitinib was administered, resulting in significant improvement at eight weeks. This case highlights atypical tinea presentations, Id reactions, and introduces upadacitinib as a novel treatment option for refractory Id reactions.
Source: IDCases
DOI: 10.1016/j.idcr.2025.e02300
Authors: Jing Mao, Zequn Tong, Xinhong Su, Zheyu Zhuang, Siyi Bao, Ying Chen, Zhixun Xiao, Ting Gong, Chao Ji
Institutions: Fujian Medical University, First Affiliated Hospital of Fujian Medical University, North Sichuan Medical University, Capital Medical University, Beijing Anzhen Hospital, Nanchong Central Hospital, Shanghai Jiao Tong University, Shanghai Children's Medical Center
Language: English
Subfield: Epidemiology
Field: Medicine
Open Access status: gold
Estimated APC paid: $1,370
OpenAlex ID: W4411508247
FWCI: 0.623
Cites: 21
Cited by: 1
Related to: 10