Work

Venous thromboembolism prophylaxis initiation in adults with traumatic brain injury: elusive and hard to pin down

Year: 2025

Type: article

Abstract: Patients with traumatic brain injury (TBI) are at high risk of developing venous thromboembolism (VTE).1 In these patients VTE prophylaxis must be weighed against the risk of intracranial hemorrhage expansions and prevention of VTE. Although the use of VTE prophylaxis has been shown to be beneficial in this population, fears of hemorrhage progression and TBI-related morbidity and mortality have mitigated its early use.2 There is considerable interest among the trauma community to identify the optimal time of initiating prophylaxis. Most centers have individualized protocols on timing and dosing of VTE prophylaxis in patients with TBI. Yet, there is a paucity of strong evidence to support earlier initiation, especially in high-risk patients with severe TBI and those who have had neurosurgical interventions.

Source: Trauma Surgery & Acute Care Open

DOI: 10.1136/tsaco-2025-001942

Authors: Michele N Fiorentino, Asanthi Ratnasekera

Institution: Christiana Care Health System

Language: English

Topic: Venous Thromboembolism Diagnosis and Management

Subfield: Internal Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,100