Work

Multi-target antibacterial Ru-based metallodrugs containing phenylsulfonyl indole derivatives: synthesis and their efficacy against Gram-positive and -negative bacteria

Year: 2025

Type: article

Abstract: A multi-target antibacterial Ru-based metallodrug containing phenylsulfonyl indole derivative (RuS2) can destroy the bacterial membrane and induce the production of reactive oxygen species (ROS) and showed significant anti-infective potency in vivo .

Source: RSC Advances

DOI: 10.1039/d5ra03098f

Authors: Shijie Lin, Guangying Yu, Liu Zhang, Xiangwen Liao, Guijuan Jiang, Lianghong Liu

Institutions: Hainan General Hospital, Hainan Medical University, Jiangxi Science and Technology Normal University, Hunan University of Medicine

Language: English

Topic: Metal complexes synthesis and properties

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,042