Intravenous Diazepam Infusion in Tetanus: An Experience in Balancing a Unique Clinical Challenge
Year: 2025
Type: article
Study design: Case Report
Abstract: sensory stimuli, and eventually led to generalized body aches, spasms, opisthotonos, and difficulty in movement.The patient had not received a tetanus toxoid in the last 5 years and denied any relevant medical history.After two brief hospitalizations, he was referred to Indira Gandhi Institute of Medical Sciences (IGIMS) due to worsening symptoms.In the ICU, wound care was provided, along with tetanus immunoglobulin, tetanus toxoid, sedation, spasm management, and airway protection with intubation followed by tracheostomy.Due to unresponsive spasm control with midazolam, diazepam infusion was started for reducing spasm frequency.Complications, including autonomic dysfunction, rhabdomyolysis, recurrent hypoglycemia, and metabolic acidosis, were managed appropriately.Blood pressure
Authors: Sanjeev Kumar, Ritu Singh, Abhay Kumar, Lokesh Kadam, Ravi P Yadav
Institution: Indira Gandhi Institute of Medical Sciences
Language: English
Subfield: Endocrinology
Domain: Life Sciences
Open Access status: diamond
OpenAlex ID: W4411570556