Work

Novel mangiferin derivatives attenuate adipogenesis in 3T3-L1 preadipocytes and ameliorate diet induced obesity in C57BL/6J mice

Year: 2025

Type: article

Abstract: /2 days) significantly inhibited body, liver and fat tissue weight gain, reduced lipid dysfunction, and ameliorated pathological characteristics in high-fat diet induced C57BL/6J obese mice. These results suggest that compound G1 may warrant further investigation as a promising anti-obesity agent for the treatment of human obesity.

Source: RSC Medicinal Chemistry

DOI: 10.1039/d5md00264h

Authors: Dong-Quan Gu, Yin Li, Liu-Shun Wu, Meng-Ting Lyu, Ying Li, Sheng-Zhuo Huang, Feng-Qing Xu, De-Ling Wu, Wu-Xi Zhou

Institutions: Anhui University of Traditional Chinese Medicine, Chinese Academy of Tropical Agricultural Sciences, Tropical Bioscience and Biotechnology Research Institute

Language: English

Topic: Mangiferin and Mango Extracts

Subfield: Complementary and alternative medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Natural Science Foundation of China, State Administration of Traditional Chinese Medicine of the People's Republic of China, Anhui University of Chinese Medicine

Awards: G2685505205, G4634466754, G7123217628, G7983103893

OpenAlex ID: W4411606631

FWCI: 3.168

Cites: 43

Cited by: 3

Related to: 10