Work

Chemical Characterization and Detergent Potential of Chelidonium Majus Extracts

Year: 2025

Type: article

Abstract: The present study investigates the impact of different extraction methods—accelerated solvent extraction (ASE), ultrasound-assisted extraction (UAE), and maceration on the yield, phytochemical composition, antioxidant activity, and antimicrobial potential of Chelidonium majus extracts. ASE demonstrated the highest extraction yield (85.7%) and alkaloid content (5.4 mg AE/ml), correlating with enhanced antimicrobial activity against Escherichia coli, Staphylococcus aureus, and Candida albicans (lowest MIC values: 3.12%, 2.50%, and 6.25%, respectively). UAE resulted in the highest polyphenol content (15.2 mg GAE/ml) and antioxidant capacity (12.8 ± 1.5 µmol Trolox/ml), suggesting its effectiveness in preserving antioxidant compounds. Maceration produced the lowest bioactive compound yield and biological activity. These findings indicate that ASE is optimal for antimicrobial applications, while UAE is preferable for antioxidant-enriched extracts. The results provide valuable insights for optimizing C. majus extraction in pharmaceutical, food, and cosmetic formulations.

Source: Studia Universitatis Babeș-Bolyai Chemia

DOI: 10.24193/subbchem.2025.2.04

Authors: Anca BECZE, Dorina SIMEDRU, Liviu BÎLTEANU, Paul UIUIU

Institutions: Research Institute for Analytical Instrumentation, National Institute of Research and Development for Optoelectronics, University of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca

Language: English

Topic: Medicinal Plant Research

Subfield: Plant Science

Field: Agricultural and Biological Sciences

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: diamond

Funder: European Commission