Prevalence of Hepatitis B Virus Infection among Pregnant Women at the Koulikoro District Health Center
Year: 2025
Type: article
Study design: Observational Study
Abstract: The objective of this study was to assess the prevalence of HBsAg among pregnant women in the Gynecology and Obstetrics Department. It was a descriptive and analytical cross-sectional study conducted from May 2019 to April 2020 in the Gynecology and Obstetrics Department of the Koulikoro District Health Center. Results: During this period, we screened 424 pregnant women for HBsAg. Among them, 68 tested positive, giving a prevalence rate of 16%. The average age of the participants was 26 ± 5 years, with extremes ranging from 15 to 37 years. About 35.3% of the women were pauciparous. Approximately 67.6% had their first prenatal consultation in the second trimester. Among them, 7.4% had a family history of liver disease. Risk factors associated with HBsAg carriage included female genital cutting, blood transfusion, and tattooing/scarification. Hepatic cytolysis was found in 19.1% of cases; viral replication was observed in 29.4%, and high viral load in 20.6%. The most common infection pattern was HBeAg-negative chronic hepatitis B. Serovaccination was absent in 7.4% of the newborns.
Language: English
Topic: Hepatitis B Virus Studies
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4411659971