Work

Beyond Dystonia: The Therapeutic Benefits of Botulinum Toxin Type A in Neurological Disorders

Year: 2025

Type: article

Abstract: BoNT type A (BoNT-A) is a neurotoxic protein produced by the anaerobic bacterium Clostridium botulinum . In recent years, BoNT-A has demonstrated substantial efficacy in the management of various diseases, particularly neurological disorders, and has served as a versatile therapeutic agent in modern medicine. This review is aimed at comprehensively examining the application of BoNT-A in various non-dystonia disorders—including hyperhidrosis, salivation, chronic migraine, trigeminal neuralgia, postherpetic neuralgia, primary tremor, depression, and Parkinson’s disease—in the field of neurology.

Source: Neuropharmacology and Therapy

DOI: 10.15212/npt-2024-0014

Authors: Yang Li, Wei Wei, Hanyu Zhu, Ying Tan, Weifeng Luo

Institutions: Zhejiang Chinese Medical University, Huzhou Central Hospital, Huzhou Normal University, Second Affiliated Hospital of Soochow University

Language: English

Topic: Botulinum Toxin and Related Neurological Disorders

Subfield: Neurology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

Funders: National Natural Science Foundation of China, Natural Science Foundation of Zhejiang Province