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Enantioselective Catalytic Three-Component Synthesis of Optically Active Propargyl Amino Ethers

Year: 2025

Type: article

Abstract: Catalytic enantioselective three-component aminomethylation of benzaldehyde as well as its methoxy-substituted derivatives and propargyl ethers with aniline in the presence of a chiral catalyst – pseudoephedrine – yielded previously unknown optically active propargyl amino ethers with high yields and a high degree of enantioselectivity. This reaction can also be used to form both C-C and C-N bonds.

Source: Hungarian Journal of Industry and Chemistry

DOI: 10.33927/hjic-2025-05

Author: Gulahmad Mirahmad Talybov

Institution: Azerbaijan Technical University

Language: English

Topic: Asymmetric Synthesis and Catalysis

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: diamond

OpenAlex ID: W4411694279

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