Year: 2025
Type: article
Study design: Case Report
Abstract: Background: Diabetes mellitus (DM) is a global health problem that has a tremendous impact on general health, especially on blood vessels, heart, kidneys, eyes, nerves, and other organs. DM cases are recorded as one of the contributors to the high number of deaths directly related to this disease, with high treatment costs. The oral cavity is one of the organs and systems affected by the progression of DM. Manifestations in the oral cavity are closely related to high glucose levels in oral fluids, decreased saliva flow, decreased pH, and decreased immunity of sufferers that support fungal colonies on the mucosa. These manifestations can be effectively and comprehensively managed in line with the patient's DM treatment. Laporan: A 73-year-old patient came to the Oral Diseases Department of RSGMP University of Jember complaining of a thick and uncomfortable tongue. The patient was taking glimepiride, an oral hypoglycemic agent, and amlodipine, an antihypertensive agent. Tatalaksana kasus: The patient underwent oral swab testing to detect fungal morphology, and was given a causal therapy of nystatin and a supportive therapy of multivitamins (Becomzet). The patient was instructed to follow up in one week. Discussion: The oral manifestation in this case is the presence of white plaque on the dorsum of the tongue, which is called oral candidiasis. Patients with diabetes mellitus (DM) with high glucose levels experience hyposalivation and changes in tissue resistance, which facilitates colonization and penetration of fungi into the oral mucosa. Conclusion: The diagnosis of this case is oral candidiasis, with the systemic etiology being diabetes mellitus (DM). The success of the treatment depends on the integration of therapy between the dentist, the doctor who treats the systemic disease, and the patient's compliance with the doctor's instructions.
Author: Leni Rokhma Dewi
Language: English
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W4411697499