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Ugi-reaction-derived ionizable lipids with cyclic tertiary amine heads enable spleen-targeted mRNA delivery

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Year: 2025
Type: article
Source: Biomaterials Science
DOI: 10.1039/d5bm00738k
Authors: Yashuai Wang, Xiaoyin Liu, Haiyin Yang, Shuxiang Wang, Shutao Guo, Yuhua Weng, Jinchao Zhang, Luwei Li, Kun Ge, Xing-Jie Liang
Institutions: Nankai University, Hebei University, State Key Laboratory of Medicinal Chemical Biology, Beijing Institute of Technology, Chinese Academy of Sciences, National Center for Nanoscience and Technology, University of Chinese Academy of Sciences
Language: English

Topic: RNA Interference and Gene Delivery
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: closed

Funders: Natural Science Foundation of Hebei Province, Hebei University, National Key Research and Development Program of China
Awards: G3758956438, G5178654611, G547324671, G8745050562
OpenAlex ID: W4411698358
FWCI: 1.529
Cites: 26
Cited by: 6
Related to: 10
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