Year: 2025
Type: article
Abstract: Aim Gentamicin is frequently administered to surgical patients for both prophylaxis and treatment of infections. Proper dosing and administration are crucial to maximize its therapeutic efficacy and minimize adverse effects. Local guidelines have been established to standardize dosing and monitoring practices. This audit aims to assess the appropriateness of gentamicin prescriptions in a surgical unit. Method This audit was conducted in a tertiary care hospital surgical unit over two months. Data were collected from gentamicin charts of surgical patients. The parameters assessed include the accuracy of initial dosages and the adherence to monitoring serum levels in accordance with these guidelines. Initial dosage accuracy was determined by comparing prescribed dosages to guideline-recommended values. Results In the first cycle, a total of 48 patients were reviewed throughout a one-week period. Initial dosage accuracy was high, with 70% of prescriptions aligning with recommended weight-based dosing protocols. However, adherence to serum level monitoring guidelines was suboptimal with only 55% of patients having serum levels measured within the appropriate timeframe. After implementing targeted interventions, including poster displays and departmental teaching, a reaudit at one and two months demonstrated substantial improvements. 92% of initial gentamicin dosages were accurately prescribed while adherence to monitoring serum levels has increased, with 78% of patients receiving timely measurements. Conclusions The audit demonstrated that targeted interventions such as appropriate visual reminders and departmental teaching, significantly improved adherence to guidelines for gentamicin prescribing.
Source: British journal of surgery
Authors: J H Choo, R Stevenson
Institution: Glasgow Royal Infirmary
Language: English
Subfield: Applied Microbiology and Biotechnology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: bronze
OpenAlex ID: W4411707817