Work

Non-Invasive Evaluation by the HEMOTAGTM Recording Device to Tailor Treatment of Acutely Decompensated Heart Failure

Year: 2025

Type: article

Abstract: recording device-A non-invasive, wearable system that measures cardiac time intervals (CTIs)-in managing patients with acutely decompensated heart failure (ADHF). The prospective, single-center study enrolled 105 patients, including those hospitalized with ADHF and a control group with non-HF-related conditions. Daily measurements of isovolumetric contraction time (IVCT), a key CTI marker, were collected using the HEMOTAG device and compared with NT-proBNP levels obtained on admission and day 3. Among ADHF patients, IVCT decreased in parallel with NT-proBNP levels, indicating volume status improvement with therapy. In contrast, the control group showed no significant change in IVCT or NT-proBNP. An IVCT ≥ 40 ms demonstrated strong sensitivity and specificity to detect ADHF (NT-proBNP ≥ 1800 pg/mL). These findings suggest that IVCT trends measured by HEMOTAG correlate with short-term treatment response in ADHF and could offer a non-invasive method to guide heart failure management. The technology demonstrated feasibility, safety, and clinical relevance, supporting its potential role in future remote management strategies.

Source: Cardiovascular Science

DOI: 10.70322/cvs.2025.10007

Authors: Robert Chait, Fergie Ramos Tuarez, Jesus E. Pino, Dipan Uppal, David Snipelisky

Institutions: University of Miami, John F. Kennedy Medical Center, Mayo Clinic, Cleveland Clinic Florida

Language: English

Topic: Heart Failure Treatment and Management

Subfield: Cardiology and Cardiovascular Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Funder: National Heart, Lung, and Blood Institute