Work

Well-circumscribed eroded lesions on the palms of a middle-aged woman

Year: 2025

Type: article

Abstract: A 58-year-old woman presented with a 2-year history of well-circumscribed erythematous lesions associated with a burning sensation on the palmar aspect of both hands. There was no history of trauma to the affected areas. Histopathological examination of the plaque on the left thenar eminence revealed a sharp step in the corneal layer with hypokeratosis in the left half of the field. There was no response to treatment with potent topical steroids, topical calcineurin inhibitors or antifungals. Owing to its rarity, this condition presents both a diagnostic and therapeutic challenge to dermatologists.

Source: Clinical and Experimental Dermatology

DOI: 10.1093/ced/llaf260

Authors: Louise L K St Aimee, Paul Craig, Hannah E Wainman

Institutions: Bristol Royal Infirmary, University Hospitals Bristol and Weston NHS Foundation Trust, North Bristol NHS Trust, Southmead Hospital, University of Bristol

Language: English

Topic: Medicine and Dermatology Studies History

Subfield: Dermatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: Eli Lilly and Company, L'Oreal USA, UCB Pharma