Clinical Problem Solving: Invasive Aspergillosis Can Exist Even If Serum Galactomannan is False Positive!
Year: 2025
Type: article
Abstract: Influenza-Associated Pulmonary Aspergillosis (IAPA) is a serious and often underdiagnosed fungal complication that can arise in patients with severe influenza, particularly those requiring intensive care. While not definitive alone, serological markers are valuable in conjunction with clinical, radiological, and microbiological findings to support timely diagnosis and guide antifungal therapy. Diagnosing IPA in non-neutropenic hosts, particularly those nearing endotracheal intubation and in whom bronchoscopy is contraindicated, presents a significant clinical challenge.
Authors: Rucha Karad, Tejas Bende, Rahul Doshi, Geethu Joe, Rajeev Soman
Institution: School of Tropical Medicine
Language: English
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W4411713605