Work

Induction of host genes by nested genes during C. elegans development

Year: 2025

Type: article

Abstract: embryogenesis, we observed that coexpression between nested and host genes is relatively common especially in cells positive for the nested gene. Our study illustrates how the presence of a nested gene can influence expression of its host.

Source: iScience

DOI: 10.1016/j.isci.2025.113021

Authors: Fabien Soulavie, Carole Couillault, Matéo Melki, Khulganaa Buyannemekh, Antoine Barrière, Paul Villoutreix, Vincent Bertrand

Institutions: Centre National de la Recherche Scientifique, Aix-Marseille Université, Institut de Biologie du Développement Marseille, Université de Toulon, Inserm, Laboratoire d’Informatique et Systèmes

Language: English

Topic: Developmental Biology and Gene Regulation

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: gold

Estimated APC paid: $3,240

Funders: Biogen, Aix-Marseille Université, Agence Nationale de la Recherche, Fondation pour la Recherche Médicale, Fondation ARC pour la Recherche sur le Cancer, National Institutes of Health

Awards: G1190173965, CenTuri : Centre Turing des Systèmes vivants, Transcriptional precision during development : the problematic case of nested genes, G4348384526, G4950536974, G5215612560, G5553438487, G7011901419, G7781963549, France-BioImaging (Biological Imaging Next-Generation Instrument), G9000028377, Caenorhabditis Genetics Center

OpenAlex ID: W4411729157

FWCI: 0.255

Cites: 47

Cited by: 1

Related to: 10