Impact of Cisplatin on the Incidence of Nephrotoxicity in Patients at the National Oncology Teaching Hospital in Al-Najaf Province, Iraq
Year: 2025
Type: conference-abstract
Abstract: Background: nephrotoxicity is one of the significant complications of cisplatin.Aim of study: to evaluate the impact of cisplatin on nephrotoxicity in patients at the National Oncology Teaching Hospital in Al-Najaf Province.Patients and methods: An observational, cohort study was conducted by 40 patients at the National Hospital for Oncology and Hematology in Al-Najaf Al-Ashraf, Iraq. Results:The study shows significant differences in urea and creatinine levels before and after cisplatin treatment with p-values of 0.381, 0.036, respectively.Cisplatin treatment significantly increased urea and creatinine levels in both genders, with females experiencing a more pronounced decrease after four months than men.Conclusion: Our findings indicate a high incidence of nephrotoxicity in Cisplatin patients, with males at greater risk than females.This is influenced by Urea and Creatinine levels before, 2 months after, and 4 months after Cisplatin treatment.
DOI: 10.21614/sgo-765
Institution: University of Kufa
Language: English
Subfield: Pathology and Forensic Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4411729628