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Primary Orbital Teratoma With Congenital Anophthalmia in a Neonate: A Rare Case With Histopathological and Radiological Correlation

Year: 2025

Type: article

Abstract: This case report describes a rare instance of primary orbital teratoma with anophthalmia in a neonate. A 6-day-old female presented with a congenital right orbital swelling and absence of visible ocular structures. MRI revealed a large, well-vascularized orbital mass without intracranial extension, accompanied by malformations in the right cerebral hemisphere. Histopathological examination confirmed a benign, mature/mixed teratoma comprising elements from all three germ layers, including neuroectoderm, mesoderm, and endoderm, with no evidence of malignancy. The patient underwent successful orbital exenteration with an implant at 3 weeks of age.

Source: Case Reports in Ophthalmological Medicine

DOI: 10.1155/crop/5032089

Authors: Dejan M. Rašić, Dolika D. Vasović, Miroslav Knežević

Institutions: University of Belgrade, Univerzitetski Klinički Centar Srbije

Language: English

Topic: Teratomas and Epidermoid Cysts

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $790