Assessing data completeness in the international society for the study of pleura and peritoneum (ISSPP) PIPAC database: a multicenter evaluation from 2020–2024
Year: 2025
Type: article
Abstract: Objectives In 2020, Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC) reached stage 2b of the IDEAL framework and a prospective international PIPAC database was launched in June 2020 by the International Society for the Study of the Pleura and Peritoneum (ISSPP). The ISSPP PIPAC database consists of six key elements, which are reported in an annual report. The ISSPP Registry Group decided to investigate data completeness within the ISSPP PIPAC Database. Methods Retrospective analysis of data completeness in the six key elements was performed between October 1st and 14th, 2024. This was complemented by an in-depth analysis of missing data in Response Evaluation, Complications, and Follow-up . Results Thirty centers, 950 patients, and 2777 PIPAC procedures were registered in the ISSPP database by October 2024. Sixteen of the 30 centers had included patients. Incomplete data were observed in four of the six key elements. Most centers (7/16) had incomplete data in Complications , followed by Response evaluation (5/16), and Follow-up (2/16). In depth analysis showed that, e.g., for complications, the date and type of the complication was registered in 88 and 89 %, respectively. Incomplete data in Response evaluation occurred mainly in the small group of patients evaluated by nonperitoneal regression grading score (non-PRGS, n=316), where no scoring was provided in 211 patients (72 %). Follow-up data, such as date of death or reasons for stopping PIPAC, were provided for 86 and 85 % of patients. Conclusions Overall data completeness of the ISSPP PIPAC Database was considered satisfactory at the present state, and the ISSPP Registry Group has launched several initiatives to further improve data completeness and quality, to provide solid data sets for future annual reports and other research.
Source: Pleura and Peritoneum
DOI: 10.1515/pp-2025-0014
Authors: Magnus Skov Jørgensen, Pernille Shjødt Hansen, Claus Wilki Fristrup, Martin Hübner, Jimmy So, Anne-Cecile Ezanno, Peter Hewett, Miguel Ruiz-Marin, Günther Rezniczek, Özgül Düzgün, Marc Pocard, Francesco Casella, Laura Lay, Marisa Aral, Tarkan Jäger, Felix Laminger, Oliver Glehen, Claire-Angéline Goutard, Laurent Villeneuve, Andrea Di Giorgio, Michael Bau Mortensen
Institutions: Odense University Hospital, Centre Hospitalier Universitaire Vaudois, Hôpital Orthopédique de la Suisse Romande, University of Lausanne, National University Hospital, Hôpital d'Instruction des Armées Bégin, Queen Elizabeth Hospital, Hospital Reina Sofía de Murcia, Universitätsklinik Marien Hospital Herne, Ruhr University Bochum, Ümraniye Eğitim ve Araştırma Hastanesi, Centre National de la Recherche Scientifique, Inserm, Université Paris Cité, Assistance Publique – Hôpitaux de Paris, Pitié-Salpêtrière Hospital, Nanomédecine, Biologie extracellulaire Intégratome et Innovations en santé, University of Verona, Universidad de Buenos Aires, Hospital de São João, Paracelsus Medical University, Hanusch Hospital, Hospices Civils de Lyon, Hôpital Lyon Sud, Agostino Gemelli University Polyclinic, Istituti di Ricovero e Cura a Carattere Scientifico
Language: English
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $1,187
Funder: Syddansk Universitet
OpenAlex ID: W4411740588