Work

Bicavitary involvement of feline eosinophilic sclerosing fibroplasia with intralesional methicillin-resistant Staphylococcus aureus

Year: 2025

Type: article

Abstract: Case summary A 4-year-old spayed female domestic shorthair cat was presented for evaluation of multiple abdominal masses and hyperglobulinemia. Thoracic radiographs and abdominal ultrasonography revealed a cranial abdominal mass with extension through the aortic hiatus of the diaphragm and into the caudodorsal mediastinum. A diagnosis of feline eosinophilic sclerosing fibroplasia (FESF) with intralesional methicillin-resistant Staphylococcus aureus (MRSA) was obtained based on necropsy results. Relevance and novel information To the authors’ knowledge, this case report is the first to describe extension of a primary FESF lesion through the diaphragm and is the first confirmed case of intralesional MRSA in an FESF lesion. In addition, this case is one of a growing number of reports of FESF lesions that do not involve the gastrointestinal tract. This case further contributes to the growing evidence that FESF should be considered as a differential diagnosis, in addition to neoplasia, feline infectious peritonitis or abscessation, in cats with masses, especially when there is concurrent hyperglobulinemia, a low albumin:globulin ratio and/or eosinophilia. This case also highlights the importance of considering this differential for masses outside the abdominal cavity, those involving both the chest and the abdomen, and those that do not involve the gastrointestinal tract.

Source: Journal of Feline Medicine and Surgery Open Reports

DOI: 10.1177/20551169251340288

Authors: Melody J Ward, Alisia Weyna, Katie L Anderson

Institution: University of Wisconsin–Madison

Language: English

Topic: Veterinary Oncology Research

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $700