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A Fatal Cascade Following Endoscopic Retrograde Cholangiopancreaticography (ERCP) Complicated by Pancreatitis, Duodenal Perforation, Gastrointestinal Hemorrhage, and Multi-organ Failure

Year: 2025

Type: article

Abstract: Endoscopic retrograde cholangiopancreatography (ERCP) is a valuable diagnostic and therapeutic procedure that carries inherent risks, with pancreatitis being a significant complication. While most cases resolve without major sequelae, severe complications can occur. A 65-year-old female with a history of pancreatitis developed post-ERCP pancreatitis following stent placement. The patient subsequently presented with walled-off fluid collections and experienced a catastrophic course complicated by duodenal perforation, severe hemorrhage, and multi-organ dysfunction, ultimately resulting in mortality. This case emphasizes the potential for life-threatening complications following post-ERCP pancreatitis and underscores the importance of vigilant monitoring and prompt intervention in managing these patients.

Source: Cureus

DOI: 10.7759/cureus.86983

Authors: Sharath Rajagopalan, Vikash Kumar, Bharath P Bhushan, Leonard R Maier, Eric Huang

Institutions: West Virginia University, West Virginia University Hospitals

Language: English

Topic: Gallbladder and Bile Duct Disorders

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4411766303