Work

BEOL Electro-Biological Interface for 1024-Channel TFT Neurostimulator with Cultured DRG Neurons

Year: 2025

Type: conference-paper

Abstract: The demand for high-quality neurostimulation, driven by the development of brain-computer interfaces, has outpaced the capabilities of passive microelectrode-arrays, which are limited by channel-count and biocompatibility. This work proposes a back-end-of-line (BEOL) process for 1024channel stimulator with bioelectrodes and waterproof encapsulation to stimulate dorsal root ganglion neurons. We introduce an active-matrix neurostimulator based on n-type low-temperature poly-silicon thin-film transistor, adding PEDOT:PSS and SU-8 as bioelectrodes and encapsulation. This enables precise stimulation of DRG neurons, addressing key challenges in neurostimulation systems.

Source: IEEE Electron Devices Technology & Manufacturing Conference (EDTM)

DOI: 10.1109/edtm61175.2025.11040178

Authors: Haobin Zhou, Bowen Liu, Taoming Guo, Hanbin Ma, Chen Jiang

Institutions: Tsinghua University, Chinese Academy of Sciences, Suzhou Institute of Biomedical Engineering and Technology

Language: English

Topic: Neuroscience and Neural Engineering

Subfield: Cellular and Molecular Neuroscience

Field: Neuroscience

Domain: Life Sciences

Open Access status: green

Funder: National Natural Science Foundation of China

Awards: G6470418393, G8107434926