Endovascular Treatment of Intracranial Aneurysms: A Two-Center Retrospective Analysis of Clinical Outcomes
Year: 2025
Type: article
Study design: Observational Study
Abstract: Objective: The aim of this study was to evaluate the clinical and angiographic outcomes of endovascular treatment (EVT) for intracranial aneurysms (IA).The efficacy and safety of coil embolization, flow diverter (FD), and coil + FD combination were examined.Methods: Between 2019 and 2022, 110 patients who underwent EVT in two centers were retrospectively analyzed.Demographic data, aneurysm characteristics, treatment modalities, and procedural outcomes were compared.The primary endpoint was complete aneurysm occlusion as assessed by the Raymond-Roy Occlusion Classification (RROC).Secondary endpoints included complication rates, neurologic outcomes, and clinical outcomes at follow-up (modified Rankin Scale (mRS)).Results: Of the 110 patients included in the study, 84.5% had aneurysms localized in the anterior circulation and 15.5% in the posterior circulation.The rates of RROC 1 were 69.8% in the coil group, 71.8% in the FD group, and 71.4% in the coil+FD group (p=0.231).Thromboembolic complication rates were higher in the FD (20.5%) and coil + FD (21.4%) groups, while intraoperative rupture rates were 10.3% in the FD group.In terms of neurologic outcomes, mRS 0-2 rates were 93.0% in the coil group, 89.7% in the FD group and 85.7% in the coil + FD group (p=0.161). Conclusion:EVT is an effective method in the treatment of IAs.Although the clinical and angiographic results of coil, IA and coil + FD combinations are similar, thromboembolic complications have been shown to be higher in the groups using IA.The need for individualized patient management and long-term follow-up in treatment selection is emphasized.
Author: Mehmet Selim Gel
Institution: Zonguldak Bülent Ecevit University
Language: English
Subfield: Neurology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4411808639