The relationship between autism and autism spectrum disorders and vaccination: review of the current literature
Year: 2025
Type: article
Abstract: This study evaluates the alleged relationship between childhood vaccination—specifically the MMR (measles, mumps, rubella) and DPT (diphtheria, pertussis, tetanus) vaccines—and the development of autism spectrum disorders (ASD). It addresses public concerns by reviewing existing literature and highlighting the essential role of vaccines in public health. A comprehensive analysis of scientific studies, including systematic reviews, meta-analyses, and population-based investigations, was conducted, with particular attention to research on temporal associations, thimerosal content, and proposed immunological mechanisms. The findings consistently show no causal link between childhood vaccinations and ASD. Neither the MMR vaccine nor thimerosal-containing vaccines were associated with an increased risk of ASD, as confirmed by large-scale cohort studies and international meta-analyses. Additionally, no evidence supports claims that temporal patterns or atypical forms of ASD are related to vaccination. Overall, the current scientific consensus strongly refutes the notion that vaccines cause autism. The findings support the continuation of current immunization programs, stressing the importance of combating misinformation, reinforcing public trust, and safeguarding community health through sustained vaccination efforts. No changes to existing vaccine protocols are warranted.
Source: Trends in Pediatrics
DOI: 10.59213/tp.2025.222
Authors: Nermin Eylül Çatlı, Gonca Özyurt
Institution: Izmir Kâtip Çelebi University
Language: English
Subfield: Health
Field: Social Sciences
Domain: Social Sciences
Open Access status: diamond
OpenAlex ID: W4411825173